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Besides, carnitine supplementation was considered to benefit CVD patients by facilitating beta-oxidation of fatty acids but recent meta-analyses revealed conflicting results [14, 15]
Targeting ligands may include monoclonal antibodies (e.g., trastuzumab targeting HER2), peptides (e.g., RGD motifs for integrins), aptamers, or small molecules such as folic acid [113,114,115,116]
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[241] [242] In contrast to human studies, adult female rats exhibit markedly greater dopamine release in the nucleus accumbens and more pronounced behavioral effects from amphetamine administration relative to males, effects that may be modulated by fluctuating estradiol levels across the estrous cycle or more broadly by adult gonadal hormones
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