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With reduced US investment in life sciences, attention is increasingly shifting to Chinas rise as a pioneering R&D and clinical trial centre, particularly at the forefront of novel mechanism of action innovation, alongside the growing influence of other innovation hubs outside the US: 1

These techniques range in complexity from power flushing the common bile duct, fluoroscopic-guided stone retrieval, exploration with the choledochoscope, and intraductal lithotripsy

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Because patients with PD already show reduced levels of protective Trp derivatives, further restriction could exacerbate this deficit and undermine AhR-mediated signaling