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Fasting triglyceride concentrations were 12% lower with semaglutide compared to placebo in controlled settings, with VLDL concentrations dropping by 21%

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So in terms of regulating blood sugar in the body, insulin obviously is important because it reduces the amount of blood sugar

Furthermore, a recent large-scale meta-analysis incorporating data from 10 placebo-controlled trials ( n = 71351), including the FLOW and SOUL trials, confirmed that as a group, long-acting GLP-1RAs, including both injectable and oral formulations, significantly reduce the incidence of MACE hospitalisation for heart failure, kidney events, and all-cause mortality in people with T2D