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2021) as indicated by their properties in boosting immunity, invulnerability and keeping up the neurological framework like vitamin B group, Vitamin B1 is an essential component for maintaining normal body homeostasis, it plays a fundamental role in reducing cellular oxidative stress, and metabolism via the thiamin diphosphate (ThDP) path (Bunik and Aleshin 2017), energy production, normal cellular functions, and development, (Reidling et al

This thiolate then initiates a nucleophilic attack on the methyl group of the enzyme-bound methylcobalamin

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Metformin can also be used to treat gestational diabetes mellitus