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Helps in connective tissue formation + helps IN wound healing

rab3a and rab3d, are ex- pressed in a rat mast cell line (RBL-2H3) and that overexpression of one of these isoforms (rab3d), as well as expression of a mutant form thereof (rab3d N135I) result in a pronounced inhibition of the Ag-triggered secretory response

Although the degree of inflammation in OA is generally lower than in rheumatoid arthritis, synovial tissue can still exhibit marked hyperplasia and inflammatory cell infiltration ( Accompanying inflammation and mechanical damage, oxidative stress and multiple forms of cell death are deeply involved in the molecular mechanisms driving OA progression ( Figure 1 )

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium