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Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced nonsmall-cell lung cancer

doi:10.1002/hep.20800

IL-1, which is secreted by macrophages and has a vital role in psoriasis immunity [22], and IL-6, which activates the JAK-STAT pathway and exhibits elevated levels in psoriasis patients lesions [23], were both significantly increased in psoriasis-induced mice

These innovations aim to enhance drug deposition and increase dosing consistency, both of which are particularly pertinent for therapies requiring rapid onset and improved intranasal targeting