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Panel 6 (Toxicity and Atropinization): lists hallmark anticholinergic adverse effects such as dry mouth, blurred vision, tachycardia, urinary retention, and delirium

While free curcumin is virtually insoluble in water and pH 1.2 buffer, encapsulation increased its solubility to approximately 7.66 mg/L in water and 1.57 mg/L in acidic buffer

Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes