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In the 24-week study of patients receiving JANUVIA as add-on therapy to insulin (with or without metformin), there were no adverse reactions reported regardless of investigator assessment of causality in 5% of patients and more commonly than in patients given placebo, except for hypoglycemia (see Table 3)

Rarely, someone might have pain in their back, chest, legs, or arms

Research A 2018 study in The British Journal of Dermatology found that harsh cleansing increased TEWL by 30% , triggering sebum overproduction

Early amylin analog development was marked by pramlintide's modest clinical impact (~23% weight loss) and poor adherence due to three-times-daily dosing