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Pairing them allows the GHRH-R signal to remain elevated while the GHS-R1a pulse is delivered on the researcher's schedule rather than on the model's circadian ghrelin rhythm

(2015) Diagnosis of non-celiac gluten sensitivity (NCGS): the Salerno Experts Criteria

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Patients on any oral antihyperglycemic agent in monotherapy (N=212) or on a PPAR agent in combination therapy (N=106) or not on an antihyperglycemic agent (off therapy for at least 8 weeks, N=34) were switched to monotherapy with pioglitazone (at a dose of 30-45 mg per day), and completed a run-in period of approximately 12 weeks in duration