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The maximum blockade achievable was estimated to be around 320%, and half of this effect could be achieved with a dose of approximately 0.25 mg TE and a specific blood concentration of 4 ng/ml

C., van Dijk, G., Woods, S

A 0.5 mg starting dose would be 10 units

To compare cellular versus whole-organismal metabolism, we tested glucose uptake and mitochondrial function, using 2-NBDG glucose uptake and MitoTracker Green multiplexed with MitoTracker Red CMXRos, as surrogate analyses for T cell metabolic fitness across conditions (Fig