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doi: 10.1210/en.2003-0007 111 UssherJRBaggioLLCampbellJEMulvihillEEKimMKabirMGet al

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Important Note on the Evidence Base Important note on the evidence base: The clinical evidence on the IGF-1 axis derives largely from trials of recombinant human IGF-1 (rhIGF-1, sold as mecasermin / Increlex), which is FDA-approved for severe primary IGF-1 deficiency in pediatric patients