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5, 10 By contrast, thick intersecting bundles, intravascular herniation, increased perivascular cellularity, and necrosis were features of malignant peripheral nerve sheath tumors

CBS and CSE have been reported to re-localise to mitochondria in response to hypoxia, a common feature of the tumour microenvironment, resulting in targeted H 2 S delivery that can stimulate ATP production and protect mitochondria from oxidative stress