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The mechanism underlying constipation relates to semaglutide's action on the gastrointestinal tract
When considering study drug discontinuation or use of rescue medication (trial product estimand results), the weight loss resulting from the use of oral semaglutide was up to 5 kg, while that associated with other active comparators ranged from 0.8 to 3.8 kg, and that associated with placebo ranged from 0.1 to + 0.6 kg [35,36,37,38,39,40]
Currently, none of these human GLP-1 medications are approved in veterinary medicine
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