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HUBERMAN: We have it in mind that it's involved in these pathways, but I should say every time we look at a given peptide, whether or not it's ghrelin or hypocretinorexin or it's GLP-1, What we find is that, again, there are these pleiotropic effects

Combining them can enhance fat loss and improve metabolic health, but may also intensify side effects such as nausea or constipation