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Statistical significance was calculated by two-way ANOVA followed by Dunnetts multiple comparisons test with Bmal1 -KO set as the reference group in a (right panel), and a and d , and ANCOVA in b , and one-way ANOVA followed by multiple comparisons in e-g

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Alternatively, the mRNA of seleno-GPxs ranking high in the hierarchy (like GPx4) is stabilized through the interaction of a selenium responsive positive regulator like nucleolin with their 3-UTR (Fig