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Imaging 48 , 28232833 (2021)

Common signs include: Fatigue Weakness Anemia Pale or yellowish skin Numbness or tingling in the hands and feet Difficulty with balance Glossitis (a swollen, red tongue) Memory or concentration difficulties If you suspect you may have a vitamin B12 deficiency, consult your healthcare provider for appropriate testing and personalized recommendations

The mechanism behind this phenomenon may involve several aspects, including oxidative stress, inflammatory responses, and accumulation of advanced glycation end products (AGEs)

The search included in vitro , in vivo , and clinical studies published between 2014 and 2025