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First, the study relied on de-identified administrative data which precluded access to patient level data such as symptom severity, medication adherence, or objective sleep architecture metrics from polysomnography

Growth hormone, released primarily during deep sleep, is a key driver of neural repair

Among patients who develop neurotoxicity, some spontaneously recover over months after the end of treatment, while others may develop irreversible peripheral axonal damage, and this different individual susceptibility is essentially unexplained

Its multifactorial origins include genetic predisposition ( Staphylococcus aureus colonization ( S