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At the same time, how the active protein, or peptide, in GLP-1 drugs such as oral semaglutide are absorbed through the gut can vary among peoplecausing differences in effectiveness and tolerability, McCoy says

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Obesity or Overweight With Weight-Related Conditions While not all GLP-1 medications are FDA-approved specifically for weight loss, some like Wegovy ( semaglutide ) are, and others including Mounjaro have shown substantial weight reduction benefits

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