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Hormone replacement therapy, or HRT, is a very common treatment method for hormonal imbalances in men and women

Tirzepatide was FDA-approved to treat type 2 diabetes under the brand name Mounjaro in May 2002, and then it was also granted approval to be used for the treatment of obesity and weight management under the brand name Zepbound in November 2023

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In addition, glucagon receptor stimulation increases energy expenditure, enhances fat oxidation, and improves lipid metabolism, contributing significantly to adipose tissue reduction (Elkasrawy & Hamrick, 2024)