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Given the secondary nature of this study and the number of statistical tests, we did not look at possible clinical/behavioral implications of these endocrine effects a relevant question that was beyond the scope of the present study and should be explored in the future

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These therapies have enhanced muscle perfusion and nutrient uptake, suggesting that the muscle loss narrative can be rewritten if the right strategies are in place

Its use in jowls is considered off label but it is very effective in this region, and in the hands of an experienced physician it should be safe