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NNMT is an enzyme involved in nicotinamide metabolism and energy-related pathways

It did not include tirzepatide products such as Mounjaro and Zepbound, which were approved for weight loss after the study period

Organic selenium (Se)-containing amino acids, such as selenocysteine and selenomethionine, can provide antioxidant benefits by acting both as direct antioxidants as well as a source of selenium for the synthesis of selenium-dependent antioxidants and repair proteins (e.g., glutathione peroxidases, thioredoxin reductases, methionine sulfoxide reductases) 71

The researchers believed this change was likely due to differences in production techniques, crop yields, strain differences and growth substrate materials