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Unlike Alogliptin, Januvia does not inhibit DPP-8 or DPP-9 enzymes, resulting in fewer gastrointestinal side effects such as nausea or diarrhea which are common with other DDP-4 inhibitors like Alogliptin

4. Volcarn 2000

The proportion of patients with improvement was defined as negative SomaSignal NASH test (predicted probability 0.05 threshold to indicate independence