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This finding aligns with previous studies demonstrating decreased GPX4 expression in aging granulosa cells or ovaries [10, 34], and suggests that melatonin may counteract this age-related decline

Lip-1 liproxstatin-1

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

Other pathogenic species that target TJ protein complexes to disrupt gut barrier integrity include Vibrio cholerae and Aeromonas hydrophila which secrete a hemagglutinin/protease and a pore-forming aerolysin, respectively, facilitating the direct cleavage of occludin (Nava et al