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However, observational studies cannot establish causation, and confounding factorssuch as differences in overall health status, healthcare engagement, or disease severitymay influence these associations

Karagiannis T, Tsapas A, Athanasiadou E, Avgerinos I, Liakos A, Matthews DR, et al

For Ozempic multi-dose pens, depress the dose button completely and keep the needle in place for 6 seconds after the dose counter shows "0" to ensure complete dose delivery

The observed reduction in NNT achieved by the inclusion of additional endpoints beyond the primary endpoint speaks to the limitations of a restricted definition of benefit