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The role of key cells and inflammatory molecules in the pathogenesis of rheumatoid arthritis (RA)

Additionally, researchers have observed interactions with the dopaminergic and serotonergic systems in neurological models, suggesting broad signaling pathway engagement

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As a major source of ROS, primarily superoxide, generated as byproducts of OXPHOS at Complexes I and III [3], mitochondria possess antioxidant systems including superoxide dismutase 2, glutathione peroxidase, and catalase to neutralize ROS