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Conclusion: Connectivity patterns differ between CPSP and NPSS patients already before pain possibly allowing pain prediction and providing targets for prevention and therapy of CPSP

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Protein-tyrosine nitration is a post-translational chemical modification process for the highly selective non-enzymatic introduction of a nitro group (-NO 2 ) into the side chain by peroxynitrite (ONOO - ), a short-lived biomolecule generated by the rapid reaction of NO with superoxide radicals in vivo 40,41

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