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Meta-analyses suggest a small but statistically significant effect on body weight, with average reductions of 1-2 kg over 12 weeks

3 Results from OASIS 4: An average weight loss of 13.6% on oral semaglutide vs 2.2% on placebo 76.3% of people on the pill lost at least 5% of their body weight Around 30% lost 20% or more For people who completed the full 64 weeks, the average weight loss reached 16.6% ATTAIN-1 tested Foundayo in 3,127 adults with obesity or overweight (with a weight-related medical problem), without type 2 diabetes

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