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While the ultimate goal of the geroscience approach is to extend healthy lifespan by delaying or preventing disease, the lack of specific biomarkers for senescent cells (fluid, imaging, etc.) represents a major hurdle for identifying participants that may most benefit from senolytics

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A single delay of one to two days will not significantly reduce your weight loss or blood sugar control

Importantly, current therapeutic approaches focus on alleviating immune-mediated injury to the kidney, mainly targeting the migratory and functional features of immune cells with little impact on fibrosis or chronicity