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According to Ramos, an intermediate -thal mouse model reveals the development of erythroid hematopoietic progenitor cells, with the expansion being significantly more prominent in the spleen than in the bone marrow ( 2.1.2 Abnormal differentiation of erythroid precursor cells Erythroid precursor cells encompass cells at various stages ranging from proerythroblasts to orthochromatic erythrocytes