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"Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance." Diabetologia

Patients come in for B12 injections on an as needed individualized schedule

2020) confirmed that B12 levels at or above 1,000 ng/L were associated with solid cancers: OR 1.96 for cancers without metastases and OR 4.21 for cancers with metastases, after adjusting for all other causes of elevated B12