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Work from David Savages group showed that PLIN1 mutations from patients with lipodystrophies, which lack the C-terminus, fail to stabilize ABHD5 on LDs, resulting in greater basal lipolysis (137) and likely explains why these patients are unable to sequester FAs into TAGs

PCAC, the Pharmacy Compounding Advisory Committee, is meeting the FDA this week 10 of 12 members on the committee work in businesses aligned with peptides The PCAC recommendation is non-bindingMy take: Let the people inject themselves through regulated channels, via licensed providers and pharmacists There are millions of people injecting themselves with grey market peptides with zero oversight

While B12 can be taken orally, injections or IVs are really the most effective, absorbable ways to get B12 into your system

H.) for use as study endpoints