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The intrinsic pathway (mitochondrial pathway) involves two primary mechanisms of apoptosis: cytochrome c (Cyt C) release and the opening of the mitochondrial permeability transition pore (MPTP) (Taneja et al., 2001)

A blinded patient-reported assessment of the effectiveness of therapy in terms of quality of erection for each of Test One, Two and Three was also conducted, with assessments completed following the completion of each VSS session, utilizing a ranking scale of 1 (worst) to 10 (best)

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40035_2025_496_MOESM5_ESM.xlsx (download XLSX Additional file 5: Table S7