tirzepatide trying to conceive GLP-1 Medications and Pregnancy: When Stop Before Conceiving Tirzepatide and Pregnancy: Safety Facts

Rocha P, Zhang J, Laza-Briviesca R, Cruz-Bermudez A, Bota-Rabassedas N, Sanchez-Espiridon B, Yoshimura K, Behrens C, Lu W, Tang X, Pataer A, Parra ER, Haymaker C, Fujimoto J, Swisher SG , Heymach JV, Gibbons DL, Lee JJ, Sepesi B, Cascone T, Solis LM, Provencio M, Wistuba II, Kadara H

A number of functions, including nerve growth, brain function, and red blood cell production, are dependent on vitamin B12

Now, dozens of these patients are suing the drug manufacturers in federal courts for not adequately warning of the potentially serious side effects from drugs marketed for intractable health problems, such as diabetes and obesity

GL is taken up from blood into hepatocytes primarily by human organic anion-transporting polypeptides OATP1B1 and OATP1B3 (Oatp1b2 in rats) (Ploeger et al., 2001)