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Both groups lost a similar amount of weight about 13% of body weight over 6 months

In the STEP-HFpEF trial of participants with the obesity phenotype of HFpEF, semaglutide improved symptoms, physical limitations and exercise function and reduced inflammation and body weight across the spectrum of obesity categories

--- Adems, en cultivos celulares y animales con diabetes, se ha observado que activa la va GLP1/GLP1R/PKA, mejorando la homeostasis de las clulas pancreticas

Clinicians should document adverse effects promptly and thoroughly in patient records, ensuring that both the clinical manifestation and the suspected causative agent are clearly recorded