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Neurological benefits including improved outcomes in demyelinating disease models point to CNS effects

Initial protocols commonly run six to twelve weeks, with longer courses for complex or chronic cases and maintenance schedules afterward where appropriate

This subtle but important mechanism enables the solution to remain stable and safe for extended periods within a sealed vial when aseptic handling practices are followed

What is measured in these rats and mice (and occasionally in small groups of human volunteers) is often not a hard endpoint like muscle strength or weight loss, but surrogate biomarkers: molecules in the blood that have an indirect link to a hard endpoint