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However, this is not a systematic review

Note, for BPC 157, a persistent effect is mandatory, as it can prevent amphetamine disturbances, reverse already advanced disturbances, and counteract amphetamine reverse tolerance even after a very long period (i.e., 46 days) [70,153] and even substitute the loss of dopamine neurons (MPTP) (note, BPC 157 counteracted tremor, rigor, akinesia, and also MPTP-mortality) [69]

If ever there was a situation that is perfect for a microarray gene chip-type analysis to identify novel genes induced by estradiol, this would seem to be it