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Compared with participants who received a placebo, those treated with semaglutide showed slower aging patterns across multiple epigenetic clocks associated with inflammation and the health of several major organ systems, including the heart, brain, kidneys, liver, blood, and metabolic system

doi:10.1016/S1043-6618(05)80044-1 9

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The activation of GIP receptors by retatrutide promotes glucose dependent insulinotropic polypeptide insulin secretion and insulin release in response to food intake, significantly improving glycemic control