When excitatory activity becomes excessive and unregulated, it can lead to hyperactivity of neurons, which results in seizures
This ROS production, linked to mitochondrial respiratory chain dysfunction, leads to oxidative damage of critical cellular components including membranes, mitochondria, proteins, and DNA (Mesa-Arango et al., 2014
Qiu XM, Lai ZZ, Ha SY, Yang HL, Liu LB, Wang Y, Shi JW, Ruan LY, Ye JF, Wu JN, Fu Q (2020) IL-2 and IL-27 synergistically promote growth and invasion of endometriotic stromal cells by maintaining the balance of IFN- and IL-10 in endometriosis
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