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Common signs include: Fatigue and weakness Neurological changes, such as numbness or tingling in the hands and feet Megaloblastic anemia, characterized by large, abnormal red blood cells Cognitive difficulties, including memory loss and confusion Early detection and treatment of B12 deficiency can make a big difference

Sterility: Sterile and non-pyrogenic

According to Phase 3 trial results in the New England Journal of Medicine , this rash affected 0.8% of participants after the first dose, and 0.2% of participants after the second shot

Porphyria: The use of diclofenac and anti-inflammatory steroids in patients with hepatic porphyria should be avoided