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Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia

Following 30 min of incubation at 4 C, extracts were cleared by centrifugation (17,000 g , 20 min, 4 C) and then supernatants were analysed by liquid chromatography and mass spectrometry (LCMS)

Our recent studies highlight the pivotal role of astrocyte-derived tonic GABA in modulating neural activity, including sensory information processing, memory formation, and plasticity

Mai L, Bao L-J, Wong CS, Zeng EY (2018) Chapter 12microplastics in the terrestrial environment