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Nausea typically peaks 24 to 48 hours after your first dose and usually resolves within 5 to 7 days as your body adapts

As a secondary goal, we explored the functional effects of NPW (indexed by relative cerebral blood flow, rCBF) on the pituitary (related to stress and HPA stimulation) [15, 19] and habenula (implicated in NAL aversion) [20]

Improvement of glycemic control and reduction of major cardiovascular events in 18 cardiovascular outcome trials: an updated meta-regression