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The manufacturers now sell direct to cash-pay patients for far less: Zepbound runs $299 to $449 per month through LillyDirect by dose, and Wegovy runs $349 per month for standard doses through NovoCare Pharmacy ($199 per month on the first two fills through December 2026)

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Length selection depends partly on body composition and injection site location, which your provider can assess during your treatment initiation visit

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