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Heres the month-by-month breakdown based on aggregate data from 338 Phase 2 trial participants: This timeline is remarkably consistent across patients

The FDA began its investigation in April 2023 with the batch testing

An overview of current management

Concentrated, buffer exchanged sample was lastly purified by size exclusion chromatography (SEC) at 4 C by injecting sample onto a Superose 6 Increase 10/300 GL column (GE Healthcare) equilibrated in SEC buffer (50 mM Tris, 300 mM NaCl, pH 7.0) supplemented with either 0.01% LMNG/0.001%CHS or 0.06% digitonin and immediately used for biochemical assay or cryo-EM grid preparation following quantification by BCA Assay (Pierce)