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In: Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e

Moreover, trimetazidine treatment has been found to attenuate insulin resistance and improve insulin sensitivity in patients with idiopathic dilated cardiomyopathy

It stimulates the pulsatile secretion of endogenous GH by the pituitary gland, which in turn activates downstream hepatic production of IGF-1