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Contact your prescriber quickly or seek urgent care if you have: Persistent vomiting or severe diarrhea Very dark urine or minimal urination Fainting, severe lightheadedness, or confusion Rapid heartbeat or concerning palpitations Tingling plus muscle weakness or severe cramps GLP-1 therapy is often manageable, but severe intolerance is a clinical issue, not something you should have to "push through." What To Do Next: Practical Steps For Tracking, Testing, And Relief If your symptoms are not emergent, the next best move is usually systematic: track what's happening, look for patterns, and bring a clear summary to your clinician

2022 Mar 15;10:2050313X221084839