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Cardiovascular safety data from published trials showed reductions in systolic blood pressure (ranging from 4.3 to 7.9 mmHg depending on dose) and diastolic blood pressure (2.3 to 4.6 mmHg reductions)

Most patients experience continued loss of 0.5 to 1.5 pounds weekly, with total weight loss ranging from 10 to 35 pounds or more depending on starting weight and individual factors

Mahmoud AM, Hussein OE, Abd El-Twab SM, Hozayen WG (2019) Ferulic acid protects against methotrexate nephrotoxicity via activation of Nrf2/ARE/HO-1 signaling and PPAR, and suppression of NF-B/NLRP3 inflammasome axis