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That's the appeal
It did not produce the magnitude of weight loss we now consider transformative, which is why it never became a mainstream drug
Although cyanocobalamin is more readily absorbed, much of it is excreted through the urine before it can reach the cells Cyanocobalamin vs Hydroxocobalamin In comparison to hydroxocobalamin, cyanocobalamin has a significantly worse absorption rate and storability, which is why today mostly hydroxocobalamin is used in B12 injections
Below, we outline some of the most notable preclinical and clinical studies related to AOD-9604's effects: In a 12-week clinical trial, participants administered 1mg/daily AOD-9604 experienced an average weight loss of 5.72lb, while the placebo group shed only 1.76lb
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