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Constipation: Some individuals may face this issue

Laurans et al

Research suggests that it may enable investigation of coordinated tissue repair, angiogenic signaling, and anti-inflammatory mechanisms through complementary pathway modulation including NF-B inhibition and cytokine regulation, supporting studies of synergistic regenerative and immunomodulatory signaling in experimental systems

This creates a clinical flow where patients initiate on oral therapy, stabilize, and either remain on pills or step up to higher-efficacy injectables based on their clinical needs, a tiered treatment model that expands the overall market rather than simply redistributing it