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Supplementary Figure 4 (A) Cumulative data showing relative concentrations of increased and decreased metabolites in R vs HC

John Rush has received consulting fees from Compass Inc., Curbstone Consultant LLC, Emmes Corp., Evecxia Therapeutics, Inc., Holmusk Technologies, Inc., ICON, PLC, Johnson and Johnson (Janssen), Liva-Nova, MindStreet, Inc., Neurocrine Biosciences Inc., Otsuka-US

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It participates in energy production in mitochondria, DNA repair, and activation of sirtuins, a group of proteins involved in regulating cellular aging