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The second is gastrointestinal inflammation: BPC-157s gastric origin gives it exceptional affinity for gut tissue, and the preclinical data on gut permeability, mucosal repair, and intestinal motility is the strongest body of evidence for this compound

Funding This study was supported by the Guangdong Medical Science and Technology Research Foundation (A2022479), the Guangdong Basic and Applied Basic Research Foundation (2023A1515011699), the University-Hospital Joint Fund Project of Guangzhou University of Chinese Medicine (GZYZS2024U08), and the Scientific Research Project of Guangdong Provincial Administration of Traditional Chinese Medicine(20251432)

Semaglutide and tirzepatide are GLP-1 receptor agonists

For example, a randomized, double-blinded, placebo-controlled trial found that lutein supplementation for 2 years raised MPOD, serum lutein levels, and visual sensitivity in individuals with early AMD [100]